Jan Zuna: Genetics Expert - Research, Publications & Contact Info

Is it possible to unravel the complexities of childhood leukemia and pave the way for more effective treatments? The work of Dr. Jan Zuna, a distinguished pediatric hemato-oncologist, suggests that it is not only possible but that significant strides are already being made.

Dr. Zuna's journey began with a strong foundation in genetics, earning his degree at the 2nd Faculty of Medicine. He furthered his studies there, embarking on doctoral research that would shape his future contributions to the field. Subsequently, he gained valuable experience as a postdoctoral fellow in London, UK, broadening his perspective and expertise in the realm of genetics and its intersection with medicine. His research focuses on the origin, development, and demise of the leukemic clone, secondary malignancies, residual disease, and the genes TEL/AML1, BCR/ABL, TEL/ABL, and MLL/cokoliv.

Dr. Zuna's professional life extends beyond his direct clinical work. He is the lead investigator on several projects, indicating his commitment to advancing research and innovation in his field. He is actively involved in research groups, including the Leukaemia Research Cytogenetics Group at Newcastle University, further highlighting his collaborative approach and dedication to pushing the boundaries of knowledge. His work has been recognized internationally as evidenced by his work in London, UK.

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His research interests encompass critical aspects of leukemia, delving into the origins, progression, and ultimate fate of leukemic clones. He is particularly interested in secondary malignancies, residual disease, and the genetic underpinnings of these conditions, specifically focusing on genes such as TEL/AML1, BCR/ABL, TEL/ABL, and MLL/cokoliv. This research directly informs the development of targeted therapies and improved diagnostic methods.

Dr. Zuna is actively involved in the Department of Pediatric Hematology and Oncology at the 2nd Faculty of Medicine, Charles University, and the University Hospital Motol in Prague, Czech Republic. His presence at the clinic is available at specific times for consultations. From Tuesday 13:00 to 14:30 and Thursday 14:30 to 16:00. This schedule is active until December 13, 2024, and then resumes from January 7, 2025.

His scientific contributions are significant, with a substantial body of work including 185 research papers that have garnered 4,334 citations and been read 14,513 times. This underscores the impact of his work on the broader scientific community. These works have been published on the linkos.cz portal.

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Dr. Zuna collaborates with fellow researchers, including Marketa Zaliova, Lucie Winkowska, Iveta Janotova, Justina Skorepova, Jan Stary, Lucie Sramkova, and Jan Trka. His collaborations extend to groups like the Institute of Pharmaceutical Biology/Diagnostic Center of Acute Leukemia (DCAL), reflecting the interdisciplinary nature of his work.

Dr. Zuna's research has been recognized by the broader scientific community, with interviews conducted related to his work. Additionally, funding from organizations such as the Cancer Council NSW Program Grant highlights the importance of his research and its potential impact on patient care.

Dr. Zuna's work is situated within the larger context of advances in pediatric hematology and oncology, where research is critical for improving outcomes. He has been involved in clinical studies, including research that tracked a group of patients between January 2000 and April 2021. Such research, and the data it generates, is vital for generating new findings and for refining current treatment protocols.

The professional network of Dr. Zuna extends to authors like Jozef Madzo, Ondrej Krejci, Zuzana Zemanova, Marketa Kalinova, Katerina Muzikova, Michal Zapotocky, Julia Starkova, Ondrej Hrusak, Jiri Horak, and Jan Trka, underscoring a strong collaborative atmosphere in the field. Their collective efforts are focused on furthering the understanding and improving the treatment of complex conditions like leukemia.

Dr. Zuna's contributions are supported by the facilities and resources of the Department of Pediatric Hematology and Oncology at the Second Faculty of Medicine, Charles University, and the University Hospital Motol. His ongoing work is instrumental in contributing to clinical advancement and medical education.

Dr. Zuna's perspective is also informed by the familial background. His father, Petr Zuna, is a professor at the Czech Technical University. His mother, Marie, is a physician. His brother, also named Jan, is a pediatric hemato-oncologist, reflecting a strong family commitment to medicine and health.

His dedication to research, combined with his clinical expertise, positions him as a key figure in the fight against childhood cancers. The comprehensive nature of his work, spanning from basic research to clinical practice, promises to bring forth significant advances in the field.

Dr. Zuna's dedication to advancing the understanding and treatment of childhood cancers is unwavering. His work, encompassing research, clinical practice, and collaboration, holds the potential to significantly improve the lives of children and families affected by these diseases.